Vitamin D Status in Sample of Iraqi Women with Autoimmune Thyroiditis

The most common cause of acquired thyroid dysfunction is autoimmune disease (AITD), which commonly manifests as Hashimoto's thyroiditis (HT) or Graves' (GD). importance vitamin D (vit D) an immune modulator has recently been emphasized in several types disorders. However, its significance illnesses not fully understood. purpose this study to investigate how affects the pathophysiology hyperthyroidism and hypothyroidism Iraqi women. One hundred women with age ranged from 18 60 years participate research, 50 them were patients, 30 patients other 20 euthyroidism served controls. Blood samples collected studied subjects determine profile [free triiodothyronine (FT3), free tetraiodothyronine (FT4) stimulating hormone (TSH)], antibodies [anti-thyroid peroxidase (anti-TPO), anti-thyroglobulin (anti-Tg), anti-thyroid receptor (anti-TSHR)], vit D, calcium (Ca), phosphorus (P) using different analysis techniques. Levels FT3 FT4 revealed a significant (P<0.01) increase decrease compared control. While level TSH was significantly decreased increased When comparison made between group group, results showed that levels higher hyerthyroidism than hyporthyroidism while lower hyporthyroidism. anti-TPO anti-Tg individuals, anti-TSHR individuals. On hand, findings hyperthyroidism. control, Ca P non-significant (P>0.01) differences found Also, Ca, hypothyroidism. Conclusion: It can be concluded Vit deficiency may act factor both hypothyroidism, status impact on thyroiditis. Keyword: Autoimmune thyroiditis, Vitamin Hyperthyroidism, Hypothyroidism, Euthyroidism